The Liver Kidney Microsomes (LKM) Antibodies test is a diagnostic blood test that identifies autoantibodies directed against liver and kidney microsomal antigens. These antibodies are commonly associated with autoimmune hepatitis, especially Type 2 autoimmune hepatitis.

This test helps in diagnosing autoimmune liver disorders where the immune system mistakenly attacks liver cells, leading to inflammation and liver damage. It is often used along with other liver function and autoimmune tests to confirm the diagnosis.

This test is recommended for individuals who have:

• Abnormal liver function test results
• Symptoms like fatigue, jaundice (yellowing of skin and eyes)
• Abdominal discomfort or swelling
• Dark urine or pale stools
• Suspected autoimmune liver disease
• Family history of autoimmune disorders

Doctors may also recommend this test when evaluating unexplained liver inflammation.